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Researchers describe genetic basis of rare human diseases

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Researchers at the University of California, San Francisco and in Michigan, North Carolina and Spain have discovered how genetic mutations cause a number of rare human diseases, which include Meckel syndrome, Joubert syndrome and several other disorders.

Chronic cocaine use triggers changes in brain's neuron structure

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Chronic exposure to cocaine reduces the expression of a protein known to regulate brain plasticity, according to new, in vivo research on the molecular basis of cocaine addiction. That reduction drives structural changes in the brain, which produce greater sensitivity to the rewarding effects of cocaine.

Breast cancer cells spread by digging their escape route

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Breast cancer cells puncture  holes into neighbouring tissues and crawl though the spaces they create to spread around the body, according to research published in the Journal of Cell Biology.

Researchers target an aspect of Down syndrome

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University of Michigan researchers have determined how a gene that is known to be defective in Down syndrome is regulated and how its dysregulation may lead to neurological defects, providing insights into potential therapeutic approaches to an aspect of the syndrome.

Researchers discover how brain cells change their tune (w/ Video)

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Brain cells talk to each other in a variety of tones. Sometimes they speak loudly but other times struggle to be heard. For many years scientists have asked why and how brain cells change tones so frequently. Today National Institutes of Health researchers showed that brief bursts of chemical energy coming from rapidly moving power plants, called mitochondria, may tune brain cell communication.

Study identifies patients who should not undergo surgery for a snapping hip tendon

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Researchers at Hospital for Special Surgery have identified a group of patients who may have increased difficulty for surgical treatment of a snapping psoas, a condition that usually develops because a teenager or young adult has a pelvis that grows faster than their psoas tendon. The study will be presented at the annual meeting of the American Orthopaedic Society for Sports Medicine (AOSSM), held July 7-11 in San Diego.

How immune cells move against invaders

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UCSF scientists have discovered the unexpected way in which a key cell of the immune system prepares for battle. The finding, they said, offers insight into the processes that take place within these cells and could lead to strategies for treating conditions from spinal cord injury to cancer.

Study points to risk factors of mesh-related complications in prolapse surgery patients

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Younger age, less prominent prolapse and concomitant hysterectomies are associated with a higher risk of peri-operative and mesh-related complications after prolapse repair with trocar-guided transvaginal mesh, according to a study presented by a Russian group at the 28th Annual EAU Congress.





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